At LD Davis, we pride ourselves on being an educational resource for our customers, our prospects and the community. Our blog is a helpful learning tool for those wanting to know more about glue best practices, news in the industry and simple answers to common glue questions. Hear it straight from the experts in every post. Subscribe to our blog updates.

Most Popular Posts

Gelatin glue is an adhesive used for various purposes, including packaging, bookbinding, and even some medical applications. However, its use in medical packaging, such as products for the recent COVID-19 vaccine packaging, may not be as commonly known. Gelatin glue has properties that allow it to withstand cold temperatures and can be used as an adhesive for some medical applications, depending on your requirements.

The Role Temperature Plays in Medical Packaging

Vaccines must be stored at specific temperatures to maintain efficacy. Some vaccines, like the Pfizer-BioNTech vaccine, require ultra-cold storage at temperatures as low as -70°C (-94°F). Modern vaccine packaging must ensure the vaccine vials are securely sealed and maintain their integrity during transportation and storage.

For vaccine packaging, especially for those that require extreme cold storage, specialized materials and adhesives are often used. These materials are chosen to ensure that the packaging can withstand low temperatures without compromising the vaccine's efficacy or the structural integrity of the packaging itself. Some adhesives and sealants are specifically designed to remain effective even at very low temperatures, and they might be better suited for vaccine packaging than traditional gelatin glue.

It's important to note that adhesive formulas are constantly evolving, and new technologies and materials are being developed to meet the specific demands of various industries, including pharmaceuticals. 

Benefits and Challenges of Using Gelatin Glue

Due to its natural origin and biocompatibility, gelatin glue has been used historically for various applications, including medical packaging. However, there are both benefits and challenges associated with using gelatin glue for medical packaging, which need to be carefully considered based on the specific requirements of the packaging application:


  • Biocompatibility: Gelatin is derived from animal collagen, making it biocompatible and generally safe for medical use. This makes it suitable for applications where direct contact with biological materials is necessary.

  • Natural Origin: Gelatin is derived from natural sources, which can be appealing for applications that prioritize natural materials.

  • Ease of Use: Gelatin glue can be relatively easy to prepare and apply, making it a convenient adhesive for various packaging processes.

  • Degradability: Depending on the formulation, gelatin glue can be designed to be biodegradable, which is important for reducing environmental impact.


  • Temperature and Humidity Sensitivity: Gelatin glue can be sensitive to temperature and humidity fluctuations. It may soften or lose its adhesive properties when exposed to moisture or heat and for medical packaging that requires stability under varying conditions.
    • Limited Strength and Durability: Gelatin glue may not offer the same level of strength and durability as some synthetic adhesives, which could be a concern for packaging applications that require robust sealing and protection.

    • Specialized Requirements: Medical packaging often has strict sterility, moisture resistance, and stability requirements. Achieving and maintaining these requirements with gelatin glue might be more challenging compared to modern synthetic adhesives designed for medical use.

    • Regulatory Compliance: Medical packaging materials must adhere to stringent regulatory standards to ensure patient safety. Using a traditional material like gelatin glue might require extensive testing and documentation to meet these standards.

In many modern medical packaging applications, synthetic adhesives and materials are often preferred due to their enhanced performance, stability, and ability to meet regulatory standards. However, gelatin glue is useful for niche medical applications where its biocompatibility and natural origin are advantageous, and the challenges related to temperature sensitivity, strength, and regulatory compliance are adequately addressed.

Utilizing Gelatin Glue in Your Production

Deciding whether gelatin glue suits your packaging production involves carefully evaluating your needs, requirements, and constraints. Research and understanding the properties of gelatin glue, including its adhesive strength, temperature sensitivity, moisture resistance, and biocompatibility, is critical to using it successfully. 

If you have questions about using gelatin glue for your packaging applications, our experts are here to help.

Contact Us Today

Topics: Adhesive Products, gelatin glue, Medical packaging